HA-Botox Product Information

What is HA-Botox?

HA-Botox is for the treatment of osteoarthritis knee pain, when simple painkillers (like Tylenol® or Advil®) or exercise and physical therapy are not enough. The treatment that’s right for you will depend on how far your osteoarthritis has progressed, how much pain you are experiencing, and what has worked (or not worked) for you in the past. HA-Botox is indicated for the treatment of pain due to osteoarthritis of the knee. Speak to your doctor if HA-Botox is the right treatment option for you.

How is HA-Botox administered?

HA-Botox is administered by your health care provider as an intra-articular injection into the knee joint.

How does HA-Botox work?

The precise mechanism by which HA-Botox
works is unknown. The fluid (synovial fluid) in your knee helps to lubricate and cushion the joint during movement. The major component in the synovial fluid is hyaluronic acid. One of the early effects of osteoarthritis (OA) is the breakdown of this fluid, making it less effective. It is thought that HA-Botox injection helps restore the synovial fluid back to a more healthy state, thereby reducing the pain of OA.

Why is my doctor recommending I receive HA-Botox?

HA-Botox is indicated for patients with osteoarthritis knee pain who do not obtain adequate relief from simple painkillers, (Tylenol® or Advil®), or from exercise and physical therapy.

Ask your doctor for additional information and discuss your treatment options.

What is HA-Botox made from?

Hyaluronic acid is naturally present in the body and its composition is almost exactly the same in all animal species – including human. It is particularly in high amounts in joint tissues and in the fluid that fills the knee joint (synovial fluid). HA-Botox is made from an extraction and purification of hyaluronic acid from rooster combs, where it is also found in particularly high amounts.

HA-Botox Treatment

Why are three or more injections required?

Clinical investigations with HA-Botox have demonstrated that three* 5 to five 6 injections one week apart provide significant pain relief and restoration of joint mobility. Completion of the full injection treatment course is recommended to achieve the greatest therapeutic benefit.

How do I know if HA-Botox is right for me?

A doctor is the best person to advise you on any course of treatment. HA-Botox is approved for the treatment of pain due to osteoarthritis of the knee in patients who do not get adequate relief from simple painkillers or from exercise and physical therapy.

Am I too old for HA-Botox injections?

There are no specific precautions or contraindications regarding the use of HA-Botox in older patients. During clinical trials, the safety profile of HA-Botox was well established in older patients (greater than 50 years old).

HA-Botox Benefits

When can I expect to experience pain relief?

Each patient’s response to HA-Botox may vary, depending on severity of your OA, degree of pain, and pre-existing medical conditions. In some patients, successful treatment may reduce pain within the first week after treatment begins. However, based upon clinical trials, patients may experience pain relief after their third injection of HA-Botox

Is HA-Botox treatment effective in knees with advanced osteoarthritis and loss of cartilage?

Clinical studies with HA-Botox have been primarily done in patients with mild to moderate OA.

What are the benefits of receiving HA-Botox treatment?

Successful treatment with HA-Botox should reduce pain in an osteoarthritic knee, resulting in increased mobility and recovery of joint function. Because it is a local treatment, HA-Botox should not interfere with any concomitant medicine that the patient may take. Please seek advice from your physician.