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Current treatments’ modalities

NSAIDs – Non Steroidal Anti-Inflammatory Drugs

• Oral: Well known potential systemic side effects: GI bleeding and gastric ulcers
• Topical: Limited absorption with consequent reduced risk of side effects

Non pharmacological treatment’s

• R.I.C.E. – Rest, Ice, Compression, Elevation
• Conservative treatments: may limit disability

Limits of Conventional Therapies

• Very often neglected, non or badly treated
• 40% lead to long-term complications: repeated sprains, unstable joints and arthritis-like pain
• Persistence of pain and dysfunction may 6 to 18 months after initial sprain
• Residual long-term symptoms and dysfunction 6.5 month after initial ankle sprain for 40% of patients
• Long-term symptoms for 40% of athletes 6 months after acute injury

Sprained Ankle – Current Treatment

Treatment depends in severity : RICE (Mild to Moderate Sprains, Grade 1-2)

Rest

Rest your ankle by not walking on it

Ice

Ice should be immediately applied to keep the swelling down. It can be used for 20 to 30 minutes, three or four times daily. Do not apply ice directly to your skin.

Compression

Compression dressings, bandages or ace-wraps will immobilize and support your injured ankle.

Elevate

Elevate your ankle above the level of your heart as often as possible during the first 48 hours.

NSAIDS

Nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen can help control pain and swelling.

Physical therapy

Rehabilitation exercises are used to prevent stiffness, increase ankle strength, and prevent chronic ankle problems